On October 14, 2024, alongside the World Health Summit in Berlin, Germany and Silver Economy Forum 2024, the Global Coalition on Aging (GCOA) convened a cross-disciplinary group of experts and leaders in Immunization Information Systems (IIS) across development, implementation, and advocacy from a diverse geographical scope, together with experts in healthy aging and policy.  Experts discussed the best practices and successful IIS, challenges, and barriers, as well as the advocacy needs for IIS as a critical public health tool to advance life course immunization, health equity, and more resilient health systems in the face of global demographic change. 

This new GCOA report distills four key takeaways and four calls to action from the roundtable discussion: 

1. IIS are fundamental to increasing vaccine coverage rates, supporting evidence-based decision-making, and enabling informed immunization policies across the life course.
2. The COVID-19 pandemic underscored the urgent need for effective IIS, revealing gaps in digital infrastructure and interoperability that hinder both routine and emergency immunization efforts. 
3. Building vaccine confidence and public trust in data privacy is critical to IIS success; meaningful engagement with healthcare providers and the public is essential. 
4. IIS require more than technical solutions—alignment and advocacy across stakeholders, from policymakers to the public, are necessary to realize their full value and drive system-wide improvements. 

The report highlights persistent data gaps, especially in adult immunization, and the need for countries to strengthen, expand, and connect their IIS to support healthy aging and resilient health systems. It calls for bold, coordinated action to prioritize IIS development, communicate IIS value, and ensure that no one is left behind in the global effort to prevent disease and promote healthy longevity.