This document, Supporting Healthy Aging with a Hospitable Innovation Environment: Consensus on Policy Reforms and Actions, outlines a set of core policy principles to enable the advancement of innovation, but also to ensure broader, deeper and more equitable access to ongoing innovation advances. It is based on insights and consensus achieved at a multi-sector stakeholder roundtable organized by GCOA in late 2021. The roundtable dialogue considered the public policy and market shifts stemming from otherwise very different, but equally visible health crises over the past four decades – HIV, COVID-19, and noncommunicable diseases – and brought about a unique joint understanding of the innovation solutions that mitigated the crises, immensely improving lives, creating value for society and providing a basis for reducing the associated economic and fiscal burdens.